Evaluation of pharmaceutical cream production debottlenecking schemes
The main objective of this work is to model and debottleneck a pharmaceutical production of an anti-allergic cream. The base case process has a minimum cycle time of 29 hours which is equivalent to 66 batches/year. Four schemes were proposed for process debottlenecking due to the anticipated increas...
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| Pengarang-pengarang Utama: | , , , |
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| Format: | Conference or Workshop Item |
| Bahasa: | English |
| Diterbitkan: |
2005
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| Subjek-subjek: | |
| Capaian Atas Talian: | http://eprints.utm.my/5366/ http://eprints.utm.my/5366/1/JullyTan2005_EvaluationOfPharmaceuticalCreamProduction.pdf |
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| Ringkasan: | The main objective of this work is to model and debottleneck a pharmaceutical production of an anti-allergic cream. The base case process has a minimum cycle time of 29 hours which is equivalent to 66 batches/year. Four schemes were proposed for process debottlenecking due to the anticipated increase of the product demand of 150% in the market. By carrying out throughput analysis study, schemes that fulfil the debottlenecking objective were determined. Out of the four debottlenecking schemes, Scheme 4 was chosen, which proposed a new blending tank and intermediate tank, showed a production increase of over 150%. |
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