Future trends in the use of biomarker based diagnostics in periodontal disease
Periodontitis is a group of inflammatory diseases that affect the connective tissue attachment and supporting bone around the teeth. Although periodontal diseases are initiated by bacterial pathogens, it is the activation and mediation of host inflammatory responses that are ultimately responsi...
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| 格式: | Conference or Workshop Item |
| 语言: | English English |
| 出版: |
2015
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| 在线阅读: | http://irep.iium.edu.my/45069/ http://irep.iium.edu.my/45069/ http://irep.iium.edu.my/45069/1/45069_supplement.pdf http://irep.iium.edu.my/45069/2/45069.pdf |
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| 总结: | Periodontitis is a group of inflammatory diseases that affect the connective tissue attachment and supporting bone around the teeth.
Although periodontal diseases are initiated by bacterial pathogens, it is the activation and mediation of host inflammatory responses that are ultimately responsible for the destructive events occurring in the periodontium.
Traditional periodontal diagnostic parameters used clinically include probing depths, bleeding on probing, clinical attachment levels, plaque index, and radiographs assessing alveolar bone levels. The strengths of these traditional tools are their ease of use, their cost-effectiveness, and that they are relatively noninvasive. There is a need for the development of new diagnostic tests that can detect the presence of active disease, predict future disease progression, and evaluate the response to periodontal therapy, thereby improving the clinical management of periodontal patients. This presentation highlights recent advances in the use of salivary and gingival creficular fluid (GCF) biomarker-based disease diagnostics that focus on the identification of active periodontal disease.
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