Model studies on construction of the oxabicyclic [3.3.1] core of the mulberry Diels–Alder adducts morusalbanol A and 441772-64-1

Preparation of the oxabicyclic [3.3.1] cores of morusalbanol A and 441772-64-1 was achieved via the intramolecular cyclization of cis–trans (endo) mulberry Diels–Alder adducts. The latter were derived from a hydrogen bond-assisted regioselective Diels–Alder reaction between a chalcone dienophile and...

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Main Authors: Tee, J.T., Chee, C.F., Buckle, M.J.C., Lee, V.S., Chong, W.L., Khaledi, H., Rahman, N.A.
格式: Article
出版: Elsevier 2015
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在线阅读:http://www.sciencedirect.com/science/article/pii/S0040403915011958
http://www.sciencedirect.com/science/article/pii/S0040403915011958
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总结:Preparation of the oxabicyclic [3.3.1] cores of morusalbanol A and 441772-64-1 was achieved via the intramolecular cyclization of cis–trans (endo) mulberry Diels–Alder adducts. The latter were derived from a hydrogen bond-assisted regioselective Diels–Alder reaction between a chalcone dienophile and a dehydroprenyl diene. Results from these studies provide important insights into the syntheses of morusalbanol A and related mulberry Diels–Alder adducts.