Neolamarckines A and B, New Indole Alkaloids from Neolamarckia cadamba.
Two new indole alkaloids, neolamarckines A and B (1, 2) were isolated from the leaves of Neolamarckia cadamba (Rubiaceae). Structural elucidation of 1 and 2 was performed by combination of 2D-NMR and circular dichroism (CD) spectra, and chemical correlations. Neolamarckine A (1) showed inhibition of...
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| Pengarang-pengarang Utama: | , , , , , , , , , , |
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| Format: | Artikel |
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2011
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| Capaian Atas Talian: | http://www.jstage.jst.go.jp/article/cpb/59/2/59_291/_article http://www.jstage.jst.go.jp/article/cpb/59/2/59_291/_article |
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| Ringkasan: | Two new indole alkaloids, neolamarckines A and B (1, 2) were isolated from the leaves of Neolamarckia cadamba (Rubiaceae). Structural elucidation of 1 and 2 was performed by combination of 2D-NMR and circular dichroism (CD) spectra, and chemical correlations. Neolamarckine A (1) showed inhibition of inducible nitric oxide synthase (iNOS) dose dependently. |
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