Andrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor-independent cell differentiation and apoptosis

OBJECTIVES: The growth inhibiting potential of andrographolide was evaluated in three acute promyelocytic leukaemia cell line models (HL-60, NB4 and all-trans retinoic acid (ATRA)-resistant NB4-R2). METHODS: In elucidating the mechanisms of growth inhibition, a special emphasis was placed on assess...

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Main Authors: Manikam, Shiamala Devi, Stanslas, Johnson
格式: Article
语言:English
出版: John Wiley & Sons 2009
在线阅读:http://psasir.upm.edu.my/13109/
http://psasir.upm.edu.my/13109/
http://psasir.upm.edu.my/13109/1/Andrographolide%20inhibits%20growth%20of%20acute%20promyelocytic%20leukaemia%20cells%20by%20inducing%20retinoic%20acid%20receptor.pdf
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