Determination of mitragynine bound opioid receptors
Mitragyna Speciosa Korth from Rubiaceae family is a tropical plant indigenous to Southeast Asia particularly in Thailand, Peninsular of Malaysia and Indonesia. The leaves have been used by natives for their opium-like effect and cocaine-like stimulant ability to combat fatigue and enhance tolerance...
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| தலைமை எழà¯à®¤à¯à®¤à®¾à®³à®°à¯à®•à®³à¯: | , , , , , |
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| வடிவமà¯: | கடà¯à®Ÿà¯à®°à¯ˆ |
| மொழி: | English |
| வெளியீடபà¯à®ªà®Ÿà¯à®Ÿà®¤à¯: |
American-Eurasian Network for Scientific Information
2010
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| நிகழà¯à®¨à®¿à®²à¯ˆ அணà¯à®•à®²à¯: | http://psasir.upm.edu.my/13954/ http://psasir.upm.edu.my/13954/ http://psasir.upm.edu.my/13954/1/Determination%20of%20mitragynine%20bound%20opioid%20receptors.pdf |
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| தொகà¯à®ªà¯à®ªà¯: | Mitragyna Speciosa Korth from Rubiaceae family is a tropical plant indigenous to Southeast Asia particularly in Thailand, Peninsular of Malaysia and Indonesia. The leaves have been used by natives for their opium-like effect and cocaine-like stimulant ability to combat fatigue and enhance tolerance to hard work. This study is designed to examine the binding affinity and selectivity of mitragynine towards opioid receptors namely µ-, δ-, and κ-receptors and the density of those opioid receptors in brain tissues, spinal cord, duodenum, ileum and vas deferens. Our results suggest that mitragynine has a high affinity to the 9-opioid receptors and brain has the highest density of opioid receptors. |
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