Optimization of an induction strategy for improving interferon-α2b production in the periplasm of Escherichia coli using response surface methodology
Induction strategies for the periplasmic production of recombinant human IFN-alpha2b (interferon-alpha2b) by recombinant Escherichia coli Rosetta-gami 2(DE3) were optimized in shake-flask cultures using response surface methodology based on the central composite design. The factors included in the p...
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| Main Authors: | , , , , , |
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| 格式: | Article |
| 语言: | English |
| 出版: |
Portland Press
2010
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| 在线阅读: | http://psasir.upm.edu.my/15962/ http://psasir.upm.edu.my/15962/ http://psasir.upm.edu.my/15962/1/Optimization%20of%20an%20induction%20strategy%20for%20improving%20interferon.pdf |
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