Comparison of two different indentation techniques in studying the in-situ viscoelasticity of the liquid crystal
Liquid crystal is a new emerging biomaterial. The physical properties of liquid crystal plays a role in supporting the adhesion of cells. Nano and microball indentation techniques were applied to determine the elastlc modulus or viscoelasticity of the cholesteryl ester l~qu~d crystals in the culture...
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| Main Authors: | , , , |
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| Format: | Conference or Workshop Item |
| Published: |
2015
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| Subjects: | |
| Online Access: | http://eprints.uthm.edu.my/6990/ |
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| Summary: | Liquid crystal is a new emerging biomaterial. The physical properties of liquid crystal plays a
role in supporting the adhesion of cells. Nano and microball indentation techniques were
applied to determine the elastlc modulus or viscoelasticity of the cholesteryl ester l~qu~d
crystals in the culture media. Nano-indentation results (108 k 19.78 kPa. N = 20) agreed well
with the microball indentation (1 10 * 19.95 kPa, N = 60) for the liquid crystal samples
incubated for 24 hours at 370C, respectively. However, nanoindentation could not measure
the modulus of the liqu~d crystal (LC) incubated more than 24 hours. This is due to the
decreased viscosity of the liquid crystal after immersion in the cell culture media for more than
24 hours. Alternatively, microball indentation was used and the elastic modulus of the LC
immersed for 48 hours was found to decrease to 55 ? 9.99 kPa (N = 60). The microball
indentation ind~catedth at the LC did not creep afler 40 seconds of indentation. However, the
elastic modulus of the LC was no longer measurable after 72 hours of incubation due to the
lost of elasticity. Microball indentation seemed to be a reliable technique in determining the
elastic moduli of the cholesteryl ester liquid crystals |
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