Garcinia dulcis fruit extract induced cytotoxicity and apoptosis in HepG2 liver cancer cell line
Garcinia dulcis or locally known in Malaysia as “mundu” belongs to the family of Clusiaceae.The study was conducted to investigate the anticancer potential of different parts of G. dulcis fruit extracts and their possible mechanism of action in HepG2 liver cancer cell line. MTT assay showed that the...
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| Main Authors: | , , , , |
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| Format: | Article |
| Published: |
Hindawi Publishing Corporation
2015
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| Subjects: | |
| Online Access: | http://dx.doi.org/10.1155/2015/916902 http://dx.doi.org/10.1155/2015/916902 http://eprints.uthm.edu.my/7439/1/mohd_fadzelly_abu_bakar_U.pdf |
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| Summary: | Garcinia dulcis or locally known in Malaysia as “mundu” belongs to the family of Clusiaceae.The study was conducted to investigate
the anticancer potential of different parts of G. dulcis fruit extracts and their possible mechanism of action in HepG2 liver cancer
cell line. MTT assay showed that the peel, flesh, and seed extracts of G. dulcis induced cytotoxicity in HepG2 cell line with IC50
values of 46.33 ± 4.51, 38.33 ± 3.51, and 7.5 ± 2.52 |
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