Investigation of 1h NMR profile of vegetarian human urine using anova-based multi-factor analysis
In this study,a technique that combined both analysis of variance(ANOVA) and partial least squares-discriminant analysis(PLS-DA) was used to compare the urine 1H NMR spectra of healthy people from a vegetarian and omnivorous population.In ANOVA/PLS-DA,the variation in data was first decomposed into...
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| Main Authors: | , , , , |
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| Format: | Article |
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Jilin Daxue,Jilin University
2011
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| Subjects: | |
| Online Access: | http://eprints.utm.my/45006/ |
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| Summary: | In this study,a technique that combined both analysis of variance(ANOVA) and partial least squares-discriminant analysis(PLS-DA) was used to compare the urine 1H NMR spectra of healthy people from a vegetarian and omnivorous population.In ANOVA/PLS-DA,the variation in data was first decomposed into different variance components that each contains a single source of variation.Each of the resulting variance components was then analyzed using PLS-DA.The experimental results showed that ANOVA/PLS-DA is efficient in disentangling the effect of diet and gender on the metabolic profile,and the method could be used to extract biologically relevant information for result interpretation. |
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